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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '382a1c1dfbf4f41c02b7518eee5c316ca239d156e98c7275526df0f5d439845f' 
  AND token = 'tIryY/w1OWFZeqR8VUa/4UaWQezBZpI8yT6rR89kpI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}