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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a73d532c484fa504c198de8de7fd6ad3cfdf27b745f8680f357ecb8f9d9ea80' 
  AND token = 'u3zzB1RcWlUjhynf89lgnAqRi9Uif7VT1S/xdLn/ui0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}