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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8459e02b93d8245ec4f7fc935acf8dd32f235b98ac33413393313c9e6eb644bb' 
  AND token = 'DHv+pJvp+ypbrekx764rba7QhVzQpF/v7GuCYPP5LE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}