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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f29f7ee88454e1646c1b0722b79d531efbc0323dfad8bee53871ae97819e4948' 
  AND token = 'RJ+86jKcMG4Z8Ae1z+D20NrCQqSrCmkiA1hbnPs2bwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}