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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022c08120539cb9f6aa113678a151d906c7a8726b90c6babd336339964fa43c6' 
  AND token = 'AwTmWSbCtb7cLQHiarP2lN7l3yzGkPOpB1vdPbKSzgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}