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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bca303f7b0be724e8f165293ca779c3f1cd81f0487e47998b6586571a154db25' 
  AND token = 'VHnGk1rv1em3PsKVGdBQHoUOmp8zoE3xoeVNJqa+8a0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}