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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aea527e01d82e641904ce325f5e9a270c135f4983428506b7f3d67a28013cf34' 
  AND token = 'W13PleT090zklExxvy6qTp9jqb9qTOi9E0y9b1MeqDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}