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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d312935c34d680a0d0a8d5e5d43b2261f96c1c0fe7ba8f257cf44f8c214c57f' 
  AND token = 'ZhRi4hM9RWlNWh4yAUNFdQz2qDCLT9eFtg+nuAxfAFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}