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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f29f87c39f9ca7bd78d8490c43a3ebe4eb5c8a89011a363ca031817a780c25d' 
  AND token = 'X+bw+cnImkXwQABPKY1l/7GQ7DBtso0XtcA1xE8/6+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}