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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '123f5ca0d22e88480d106ce59bc2fcc6743c58df37945676ec27353d1f6c429c' 
  AND token = '2IsGy0eASN+mpGa6wZ4Qg/FH/Z6MEJfBqa+ch/LTCAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}