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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb3e5e9321ffd7ee96576af8f5d8c28c4303700974a4f6cc43cd40c42acc18b' 
  AND token = '3nXYG8iO8cY7opVIswH3RtrHObBEFqmTSjXSBtqsMfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}