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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec0ea52c556e465537118d47510592f2eab3cc4a1826464e0f419c2244ca1f22' 
  AND token = 'WYbwrObqpjNfMQmxww/1qg3h2jNdvfQegX2Yn9a+Fzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}