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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ed64383f40ceb6a4eeb688d6397a04decdd932aeab6a1c049d389a4f155782' 
  AND token = 'mD86qD7N+ubjpbF0JvtqwHLvd30/AWgfSHjOpT16Nec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}