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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f15a690d31e9551726fbd18448e291bc2143e00d1075dc5463a582f60311e7' 
  AND token = 'ZDSGonqPZeQDxvcw3CD7mtb1tmrTDoXytHFbeD5QK6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}