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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e46ec430c45d873eb7c24f66e030ac15f3a7e80163d8b5198552cde0416e4df' 
  AND token = 'QABw33QYrBjmr1MOx3K93dOaiFK+ifjbYAm5rcFoKEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}