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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3cb1f09823d27c65b6088a1523f65c3344a3e055514d561251052b087601d2' 
  AND token = 'hq8unFq+EZADKAO4pPCQUT9L3wsG5K5iuUcFIEk8Lss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}