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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48ef8b87cf373773e04c89e9bde9744c126f720aeb99745e15d41fba4aa3f9ff' 
  AND token = 'oFZ+xiOrjaA6FOMGd+Gc83wYvTSgxfsjY1ckBHR6nKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}