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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a2136add5b7ece2bdd440c406575506dd9f64f8339d57156bbf7be3c6d64bc8' 
  AND token = 'akUkkHv5m4QpkYZojQGbQxkvp027tIvNgn0+tvDldcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}