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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6464a9d0bafb7e45e203a56e101480046f8dc498aa9590270bc75969da8dddc' 
  AND token = 'gNHq/R4vpy5WX9y54kngQEz3CExg/pzUZ1/cJPZLq1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}