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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f69d6b04e488fe0859f1f4087de08a55e0d2352716bada0c504afcf8181d894' 
  AND token = 'M6AkZzreYY/+emeExCAGvFKtqyXvEginW3Ccj2yoLeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}