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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b801e06bfb32fa9148725409632f49f59163f124992adff1f7cb3610922b2f60' 
  AND token = '5J5u+AlG9dSHmIk66AR8Nm71aYVQTULCGE4PETbsTgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}