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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3049369df87126cba9ea75e77701278e22b4521d289aa2d680d2510324c6ec8e' 
  AND token = 'BQKHPbXfjbKItCXt2hqsjcBQQ9AitRTMUaBFvuOLWmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}