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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7067e921009182b62dff2896fb4993c751af86da72a49fe4d44abc9e8bdf7c61' 
  AND token = 'm4tpxbCKBfMLF0k9YOdO8ch+FAeiii8wKCNqcrv45aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}