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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99c4541c4fcf24028d695c7b8cfcf989d7b3fa4042c83cce2c8222eb99163536' 
  AND token = 'u0bdBGRk+rbBsb8eOrSmV/7baueEwcw08A3ucWg9fSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}