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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '803dc39e2401ddb4f7d1ef32a3e804feb362ee9829a528cecf36235d99187e01' 
  AND token = 'uwJAKV/Z5axPF+wCFzmq5bU7KPTnyeUmezcTrA3k4SU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}