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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f73c04a69ec7b73c4fdb4f0e0d36b64cb653aaa94136cb267890a5e24fa18679' 
  AND token = 'A7zRRfG9Lg1yb+uPmOVsY+e+crdthM6HL3+X6bIZeq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}