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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a05ac020a2743109c18cce86254b737b95fec6e49dfb9eb9b046183d8e3bc82' 
  AND token = 'kGYeH6K/B6TI8UbMi14beDJqy+NpK2W1ETtlF1M0wG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}