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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b136a00ffa728c529d0b64a53534e9182158721dbf3f88e9da982b2575947f3' 
  AND token = 'PZkbngyTYi37FnycRNl6Z38dN995JlCuIDxs0kszhmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}