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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cdd8659022d0fc356bb402fa46871f6c6290a1c20b9c4dfc4350c0889e792ca' 
  AND token = 'X5kk07SwWY4yZuaXbe2hL9nMsau4RqcAntLoMIqJz2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}