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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de4b29ad97bc226ceadf72e9ec58b5b72178cb6b733ec01fb05d483ddb090d72' 
  AND token = '2mdMBDT9HKWZmWPYDnCO/bjmhLM+axZxPN75fDrHM64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}