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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380873231485df2daba7ecddf87867661fa73f65aeeb1d575cb7a8090828aa46' 
  AND token = '2k66mTDmzkophYI/dB9Lb5vCfqfaEpckwglykkVGid8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}