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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd6e5f97d455748c02754a5a8bbf4aef2a2faf29bebb956c4c302328ba4c3a52' 
  AND token = 'wy9a6GSSQawexXO558UxWsYnEO5LRC5vFVODmuaABT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}