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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a53d869add72b7e631a82e956fee545e97a4f65992cb4117494a83fc201a6dd1' 
  AND token = 'b1ByNPkgdkr22Drn1x9X1c3QpDoMpVZ/83L7dx0o1Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}