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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c621e86f3ee89e51f73503d453cfee2032e2d30e6b05eadf11409dcf10064a20' 
  AND token = 'EdZ2Z7fWpqg/j4XrDiC1WlGrU3h6Be6onto6xDmgJzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}