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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95a749a5b9554b140ce8730a0b216f107c78c08dfa7e2ac36fbbae55c7e48b2a' 
  AND token = 'FR2KZT3sEXi9yUaAPHKx/+5YXau1zBpwdRWukzeMtQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}