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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '454d95a9ecba0495ec0fbfbfcdd2557ee0d6648982463228e710221b2282f90e' 
  AND token = 'GS+zLvkFQqMsz1FVHZZ5Iyhhc08keWB3mJodMseEpOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}