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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '399b8c7c5ae9b808dd0b274b94e8e3bec9dc10a44b9472bbdc7ea068745f1d78' 
  AND token = 'IrE64INShyynboRytqE54AmluW7fFZ2i/sb8teKtdIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}