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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a784463cad298636734c134e2efd0aee8e0e79e5bd6b1c91f46cb1ed5e1a3f8b' 
  AND token = 'Shv2xxbsfwYIRo8QET1TeElRhdVb3ty+4HZd4tb4do0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}