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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1648a79fcefe8c2a9fe5f3a71ffc04268c45457a020ec39206b3cbc2c59a08f' 
  AND token = 'nbe/nKoLMoTq8JoIPu38bqqW6vdUU/qP6eOTJMg8igA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}