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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfdceb252aac58eec676dab1ba49d69d565c1e30b79b7a5a1c1109482a9e5a9e' 
  AND token = 'DYJHGjZ/IPi1AXzS58i89GCBmld8uxdZwagXbQAMxf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}