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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a186453d8ef2a0d514a44642de5616928bf8b82536bdc8e207fdeb982eb4832' 
  AND token = 'dGG8GRhUeumx0odu8wM3LGuQeUoZESYHjpv9KjIabSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}