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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265f6098ad8f31b172a0b18f9f17f40675d58d3adcb92e91cccbc2ef021865eb' 
  AND token = 'Ueu4MGxfKTtIst8wPZGHs0mfnx5+R2z62qNaSEPzq+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}