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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9194f9c833b6cfd235e1fd74e4b276885e5bb2741c1344b9b15ecc97f0bd66f5' 
  AND token = 'ZVow+5FuZM1LTkKL7NUx0MygZd61xcuRopLDyGtDE7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}