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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f78a50168b95bf347419570f9a6b24c588b9edf253889529369dc9e4b2215076' 
  AND token = 'zqH60XYHwXredlPZUo4a6y753F/4R9Ugmho/i7Ae77U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}