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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd1abf88cdb4f747df32d3c05738025bd5374c6b674554250521bacc14bc0c89' 
  AND token = '3txNrd92ZvzjYQg2B0WLWWQzwtcV5MmZy2zVBN03aRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}