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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d18051393f69cffa8e12329d6d93caebd04b01e095ac31cf601a8227f3c08e' 
  AND token = 'gJgwQqQ3vS1PCEvA327dcZQSoj5Vzlf9uUngCV4P3S8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}