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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e90b2426d33eceffe7f81ec27bf9373bc36c64cfea1366c5691896fdcce581bb' 
  AND token = 'vUM5x78694nrSNcSxFtaTJ8zrbuiovEXBx1yT0R9Es8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}