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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3acb0d65a6493db1af24f7823aceca60085444b7b127a126b6570a2391a83de6' 
  AND token = '/kqXzy9oLhdSkZZB11TWc7+U7sMUdLRfW9L1vDA6beo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}