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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14c9647ce1619cd3cc4095ac65ec78e332b362fd649618938ecbd63c938422b' 
  AND token = '6rW1TGDTZyQuGyjmjg/Nr5penDu1PX3J3guHhWuO4Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}