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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a464ca75c703df3225abe936b972b403495b261e7621a04c3e66c6444b05f96' 
  AND token = 'MU5kqgWotjeamxHx9kV9OtSVVHXSuRc7mx6EqA+XkFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}